Revolutionizing the
treatment of Heart Failure

Addressing the Millions of Patients with Heart Failure with Preserved Ejection Fraction

_ About Heart Failure _

Over 64 Million Patients Worldwide suffer from Heart Failure 1

There are different types of heart failure:

HFpEF IS A LARGE AND GROWING PROBLEM

Roughly 50% of people with heart failure are diagnosed with HFpEF and incidence for HFpEF continues to grow and outpace HFrEF 2

Multiple risk factors lead to increase morbidity and mortality for patients. Risk Factors include:

treatment options

Effective solutions for the treatment of HFpEF are very limited

There are no medical therapies that reduce mortality 3

Medical device implants can be an option for some, but have shown limited benefit and have increased risks 4

Surgical options are severely limited, with heart transplantation recommended only if severe and debilitating 5

A MINIMALLY INVASIVE PROCEDURE FOR THE TREATMENT OF HFpEF

Research & Development

Heart Failure Solutions is pioneering a solution that is designed to be used in a minimally invasive procedure that would how the heart functions during diastole or when the ventricle is relaxed and filling. Heart Failure Solutions is pioneering a solution that would expand the treatment options for these patients.

References

1. Teramoto, K, et al. Epidemiology and Clinical Features of Heart Failure with Preserved Ejection Fraction. Cardiac Failure Review. 2022;8e27.

2. Clark, K. and Velazquez, E. Heart Failure with Preserved Ejection Fraction. JAMA. 2020;324(15):1506-1508.

3. Kataria, R. and Van Spall, H. Pharmacologic Treatment for HFpEF: Role of Drug Therapies at the Higher End of LVEF Spectrum. American Academy of Cardiology; Expert Analysis. 2022.

4. Borlaug, B. and Colucci, W. Treatment and Prognosis of Heart Failure with Preserved Ejection Fraction. UpToDate. September 30, 2022.

5. Hajouli, S. and Ludhwani, D. Heart Failure and Ejection Fraction. In: StatPearls Publishing; 2022; updated August 2022.